The pros and cons of noninferiority trials.
نویسنده
چکیده
Noninferiority trials comparing new treatment with an active standard control are becoming increasingly common. This article discusses relevant issues regarding their need, design, analysis and interpretation: the appropriate choice of control group, types of noninferiority trial, ethical considerations, sample size determination and potential pitfalls to consider.
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ورودعنوان ژورنال:
- Fundamental & clinical pharmacology
دوره 17 4 شماره
صفحات -
تاریخ انتشار 2003